NWO-SB Programme
NWO approved a € 1.25M grant to NISB in order to initiate and stimulate collaboration in the field of Systems Biology between the three NISB partners located at the Science Park: UvA-SILS, FOM-AMOLF, and CWI. These funds are invested in a (new) NISB junior research group, in three NISB Glue Projects, and in developing the NISB organisation.The VU, as fourth NISB partner, paralleled this grant with a € 0.6M investment in a senior research group.
Junior Research Group
The research topic of this group is "Systems Biology of Molecular Regulatory Networks", which falls right in the heart of the NISB research programme. The PI establishes and maintains close interactions with research groups of all four NISB partners.
The groupleader Dr Frank Bruggeman was appointed as of 2007 October 1, employed by the CWI and UvA jointly.
MSc Anne Schwabe was appointed at the CWI as PhD student by 2008 November 1
Read more at www.cwi.nl/~bruggema.
Glue Projects
The aim of the Glue Projects is to strengthen interactions between NISB groups with complementary expertise. Glue Projects fit in the very heart of the NISB Research Programme and combine model-driven wet research with data-driven dry research.
NISB funds three Glue Projects (2008-2012) with a total budget of € 525K. Each Glue Project is executed by a PhD-student (4 year appointment) or a PostDoc (about 3 year appointment).
The following Glue Projects are currently running:
- Systems biology of the synapse: from the synaptic interactome to a mathematical model for synaptic plasticity.
- Transcriptional traffic jams: control of stochastic transcriptional bursts by transcription initiation or pausing RNA polymerases?
- The gene-regulatory potential of epigenetics: detailed analysis with a synthetic epigenetic gene network.

